Biology

2020, Biology, Slovenia / 19.07.2021

Adolescents represent a considerable percentage of cannabis users, but the effect of smoking on their pulmonary function has not yet been investigated. Therefore, I decided to compare forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) of cannabis smokers with combined cannabis and tobacco smokers and control group of non-smokers, all participants being 18-year-old males. In previous...

2020, Biology, Poland / 19.07.2021

Senescence is a state in which cells stop dividing but are metabolically active and release tumour-promoting factors. Chemotherapy can induce transient senescence of cancer cells, which may influence cancer relapse. Hence, eliminating senescent cancer cells with senolytics has potential in anticancer therapy. A process called autophagy may affect the action of senolytics. In my project, I observed that fisetin reduces...

2020, Biology, Israel / 16.07.2021

Although much is known regarding stem cell (SC) self-renewal and differentiation, the specific mechanisms used for their elimination is still unclear. One key pro-apoptotic protein is ARTS. We showed that the absence of ARTS in mice protected intestinal stem cells from apoptosis (cellular suicide), which prevented radiation-induced cell death, as well as enhanced regeneration. We also identified a novel compound...

2020, Biology, Finland / 16.07.2021

DNA of living organisms are a sensitive target for the Ultraviolet radiation, and especially UVC and UVB brings significant damage to the DNA. Fortunately, living organisms have repairing mechanisms to maintain genetic diversity and be able to reproduce. This experiment compares the effectiveness of two of these repairing mechanisms of DNA, Direct Reversal repair and Nucleotide Excision repair. The findings...