Although categorizing stimuli is a basic cognitive ability, the neural mechanisms of categorization and category learning are poorly understood. Here, we conducted a proof of concept experiment and were able to show that mice can learn categorization of auditory stimuli. This allows us to use mice as an animal model for future categorization studies. We further investigated connections in the...

Although much is known regarding stem cell (SC) self-renewal and differentiation, the specific mechanisms used for their elimination is still unclear. One key pro-apoptotic protein is ARTS. We showed that the absence of ARTS in mice protected intestinal stem cells from apoptosis (cellular suicide), which prevented radiation-induced cell death, as well as enhanced regeneration. We also identified a novel compound...