The dynamic effect of oxytocin treatment on autistic-like behaviors in a genetic model of autism
"Autism spectrum disorder (ASD) is a heterogeneous condition with no efficient treatment targeting its core symptoms available. This project aimed to investigate the dynamic changes in long-term effect of a subchronic intranasal oxytocin (0.8 IU/kg) treatment during the treatment period and after its termination in the Shank3 deficient mouse model of autism. Our results indicate prosocial and anxiolytic effects of...