Medicine

2021, Medicine, Slovakia / 20.07.2021

"Autism spectrum disorder (ASD) is a heterogeneous condition with no efficient treatment targeting its core symptoms available. This project aimed to investigate the dynamic changes in long-term effect of a subchronic intranasal oxytocin (0.8 IU/kg) treatment during the treatment period and after its termination in the Shank3 deficient mouse model of autism. Our results indicate prosocial and anxiolytic effects of...

2021, Medicine, Romania / 19.07.2021

The aim of our project is to analyse the use of equivalent electrical circuits in the modeling and study of demyelinating diseases. Within that scope, we have carried out a study into the anatomy and physiology of the nervous system, and more importantly, of the myelin sheath. Afterwards, a geometrical, a mathematical, and an electrical model have been used to...

2021, Latvia, Medicine / 19.07.2021

Mosquito-borne diseases such as Tularaemia, Sindbis virus, Dengue fever, Zika virus, Yellow fever and Malaria are spread from endemic countries to other parts of the world and climate change might be one of the main causes of this phenomenon. Research highlights that climate change is not the only factor contributing to the spread of these diseases. The study analyzes the...

2021, Hungary, Medicine / 19.07.2021

Epithelial-mesenchymal transition (EMT) contributes to the development of cancer metastases. Our research group built a new, multicellular network model of the process in order to find new possible drug-targets for the abrogation of metastases. My aim was to find a possible drug-target for the treatment of hybrid EMT cells. This phenotype was built in the model and cell-cell simulations were...

2021, Egypt, Medicine / 19.07.2021

Upper limb impairment and deterioration of motor function require rehabilitation by professional therapy to restore the limb function partially or entirely. Due to limitations in the number of therapists among other factors, much research has been conducted into robot-assisted rehabilitation of upper limb impairment. A new low cost, portable exoskeleton for hand impairment is presented in this project. This exoskeleton...

2021, Canada, Medicine / 19.07.2021

There are over 240 million cases of preventable blindness globally. Many eye diseases are “silent-killers” of vision and current testing methods are often inaccessible for marginalized patients. Thus, diseases go undetected until it is too late. To combat this issue, I developed Speculor combining low-cost portable retinal imagers and smartphones with artificial intelligence algorithms. Imagers have been tested in a...

2020, Medicine, Slovenia / 19.07.2021

Oxidative stress is defined as a disruption of the balance between production of reactive oxygen species and the body's ability to fight them off. They contribute to many autoimmune diseases, which have in the past been treated with anti-TNF therapy using inhibitors of said cytokine. So far, research has shown, that anti-TNF therapy lowers oxidative stress in patients with Crohn's...

2020, Luxembourg, Medicine / 16.07.2021

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by motor neuron death in the brain and spinal cord. Though cell death in ALS is poorly understood, scientists believe that apoptosis and autophagy play a role. The MAP4K4 kinase regulates these and its inhibition has slowed ALS in ALS-derived Induced pluripotent stem cells, iPSCs. This project examines the pathogenesis...

2020, Lithuania, Medicine / 16.07.2021

Now and especially in the near future, one of the most striking dangers to the world, which we have to overcome immediately, is environmental pollution. There are many sorts of contaminants, however, among them, pet excrements are highly harmful. I studied uncollected pet excrements in order to reveal a potential spread of deadly diseases that could escalate into an outbreak...

2020, Estonia, Medicine / 16.07.2021

Persistent cytomegalovirus (CMV) infection is one of the drivers of immunological ageing, which impairs the immune function of elderly people. In this study we show that higher anti-CMV antibody levels are associated with several chronic diseases in old individuals. We found that people diagnosed with either type 2 diabetes, chronic kidney disease or disorders of the thyroid gland had significantly...